Intermittent fasting from dawn to sunset for 30 consecutive days is associated with anticancer proteomic signature and upregulates key regulatory proteins of glucose and lipid metabolism, circadian clock, DNA repair, cytoskeleton remodeling, immune system and cognitive function in healthy subjects

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https://www.sciencedirect.com/science/article/pii/S1874391920300130

In summary, our results suggest that 30-day intermittent fasting from dawn to sunset can be a preventive and therapeutic approach in cancer as well as in several metabolic, inflammatory and immune diseases, Alzheimer’s disease and neuropsychiatric disorders by resulting in a proteome protective against carcinogenesis, obesity, diabetes, metabolic syndrome, inflammation, cognitive dysfunction, and mental health. Further studies are needed to test the effect of dawn to sunset intermittent fasting in larger cohorts with consideration given to shorter durations of fasting and longer longitudinal follow-up after completion of intermittent fasting.

Interesting study looking at 14 participants during Ramadan who fast during daylight hours. The protein expression at the end of the study was more associated with that of patients who have less cancer, Alzheimer’s, and other metabolic disorders. This doesn’t mean they actually had less illness but it seems that physiologically the fasting improved their cellular health. This might lead to less illness as they age.

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