Intermittent fasting from dawn to sunset for 30 consecutive days is associated with anticancer proteomic signature and upregulates key regulatory proteins of glucose and lipid metabolism, circadian clock, DNA repair, cytoskeleton remodeling, immune system and cognitive function in healthy subjects

https://www.sciencedirect.com/science/article/pii/S1874391920300130 In summary, our results suggest that 30-day intermittent fasting from dawn to sunset can be a preventive and therapeutic approach in cancer as well as in several metabolic, inflammatory and immune diseases, Alzheimer’s disease and neuropsychiatric disorders by resulting in a proteome protective against carcinogenesis, obesity, diabetes, metabolic syndrome, inflammation, cognitive dysfunction, and mental […]

Nutritional Ketosis and Intermittent Fasting

Over the last week I’ve documented my progress into nutritional ketosis through a ketogenic diet. Yesterday, I added intermittent fasting to that process. Here are the results. As most of you know, I have advocated for low carb high fat nutrition to reverse metabolic disease since I began practicing it myself in 1999. My understanding […]

Nutritional Ketosis, Days 5 & 6

I didn’t get a chance to update the daily posts yesterday as the start of school, high school sports practice, and school supply shopping made for a long day. Regardless, the data hasn’t changed much. I had about 29 net carbs Sunday and 22 net carbs Monday. This produced very stable blood sugar results as […]

Fasting, Irradiation, and Cancer

I wanted to share this week’s email from Peter Attia, MD. It’s a fascinating read about the protective benefits of extreme fasting in mice when they were subjected to a lethal dose of radiation. As he notes in his writing, what happens in mice cannot be directly translated to humans. We’re different species but it […]

Nutritional Ketosis, CGM Day 2

Wednesday was day two of documenting my journey into a nutritionally ketotic state of metabolism. As I mentioned yesterday, the body stores glucose which must be utilized prior to becoming fat adapted. Certain cellular machinery must be upregulated to mobilize fat from storage and allow it to enter the energy generating chemical pathways more efficiently. […]

IDM: Women and Fasting: Top Tips for Women Going Through Menopause Part 2

I’ve seen this same observation time and time again. Since using a CGM with most of my patients I’ve begun noticing how often artificial sweeteners cause a reactionary drop in glucose. Presumably this is from the body producing insulin assuming that the sweet taste represents a usable sugar. Since there is no increase in blood […]

The Truth Behind What Intermittent Fasting Does to Your Body | Inverse

Studies show intermittent fasting can lead to weight loss, stabilized blood sugar, reduced inflammation, improvements in memory and stress resistance, slowed aging, longer lifespan, and blood sugar stabilization — all promising health benefits in return for considerable lifestyle changes. — Read on www.inverse.com/article/57625-what-intermittent-fasting-actually-does-to-your-body Decent article on fasting if you ignore the unsupported semi-vegan dietary recommendation. […]

CGM Day 9 & 10: Minor detour for ice cream

Did great yesterday until the end of the day when I succumbed to the siren call of ice cream after a very long day. The breakfast spike was due to my infatuation with blueberries. Today was a new day though. I had my typical Wednesday breakfast at Nick and J’s Cafe of three eggs over […]

Day 2 of CGM

Here’s the majority of today’s readings. You can see small impact of breakfast which was the same 3 eggs and 1/2 cup blueberries as yesterday but no toast or jam. What a difference that made. Note too the dip in my glucose right before awakening and the rise as I got up. The normal stress […]