Does Vitamin D supplementation harden your arteries? Probably not.

In this population of community-dwelling adults who were vitamin D replete at baseline, supplementation with vitamin D 400, 4000, or 10,000 IU/day did not have differential effects on the development or progression of arterial calcification over 3 years.
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This study looked a group of healthy volunteers with an average Vitamin D level in the low 30s ng/mL and studied the change in arterial calcification based on a 1:1:1 randomization of Vitamin D supplementation over three years. No change was seen due to the dosage of supplementation.

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